Dropping Hemoglobin- Not just Anemia can be Thalassemia
THALASSEMIA Thalassemia is a inherited blood disorder in which mutated genes are passed from parents to children, where hemoglobin formation process is disturbed. Hemoglobin is the pigment present in blood which gives blood its color and make it rich in oxygen which provides oxygen to each and every cell of the body. So this implies that defective hemoglobin can lead to serious problems. Synthesis of Hemoglobin:- The two main components of hemoglobin synthesis are globin production and heme synthesis . Globin chain production occurs in the cytosol of erythrocytes and occurs by genetic transcription and translation. Many studies have shown that the presence of heme induces globin gene transcription. So any mutation observed in the formation of globin chain leads to the defect named thalassemia. Types of...